Unveiling Long-Term Side Effects Of Topical Corticosteroids In Eczema Treatment

Eczema, a common skin condition characterized by inflammation and itching, affects millions of individuals worldwide. While there are various treatment options available, topical corticosteroids have long been a go-to solution for managing eczema symptoms. However, recent concerns have emerged regarding the prevalent use of these medications, as their long-term side effects can sometimes outweigh their benefits. 


The Role of Topical Corticosteroids: Topical corticosteroids are anti-inflammatory medications that effectively reduce itching, redness, and inflammation associated with eczema. They work by suppressing the body's immune response and can provide significant relief when used as directed for short periods. However, their widespread use raises concerns about the potential consequences of prolonged and indiscriminate application.




  1. Skin Thinning (Atrophy): 

One of the most recognized long-term side effects of topical corticosteroids is skin thinning or atrophy. 

Prolonged use can weaken the skin's structure, making it more fragile, easily bruised, and prone to tearing. 

  1. Tachyphylaxis: 

Over time, the body may become less responsive to the medication, leading to a phenomenon known as tachyphylaxis. 

This can result in reduced efficacy, forcing patients to use stronger corticosteroids or higher doses. 

  1. Telangiectasia: 

Prolonged use of corticosteroids can lead to the development of telangiectasia, visible blood vessels on the skin's surface. 

These dilated vessels can be unsightly and difficult to reverse. 

  1. Striae (Stretch Marks): 

Corticosteroids can cause the skin to lose its elasticity, leading to the development of stretch marks, especially in areas with frequent application. 

  1. Perioral Dermatitis:

Some individuals may develop a condition called perioral dermatitis, characterized by redness, bumps, and irritation around the mouth, with prolonged use of corticosteroids. 




1. Hypothalamic-pituitary-adrenal axis suppression 

Suppression of the stress or Hypothalamic-pituitary-adrenal (HPA) axis results in inadequate cortisol production. 

Cortisol is the natural stress hormone found in humans. When this hormone is produced insufficiently, response to stressors (e.g. trauma, surgery, inflammation) may be impaired and defense against infections may be inadequate 


2. Topical Steroid Addiction/Withdrawal (TSA/TSW): 

Long-term use of potent corticosteroids can lead to a phenomenon known as TSA/TSW. When individuals attempt to discontinue corticosteroid use, they may experience severe flare ups, redness, burning, and intense itching, which can be distressing and challenging to manage. 

Balancing benefits and risks: It is essential for healthcare professionals and patients alike to recognize that topical corticosteroids are valuable tools for managing eczema symptoms, especially during acute flare-ups. However, their prolonged and indiscriminate use should be approached with caution due to the potential for these long-term side effects. 


Alternative Treatment Options: 


1. Non-steroidal anti-inflammatory creams may be considered for long-term management.

2. Emollients and moisturizers can help maintain skin hydration and act as a complementary treatment to corticosteroids.

3. Phototherapy, under the guidance of a dermatologist, can be effective for some individuals with severe eczema. 


While topical corticosteroids play a crucial role in managing eczema symptoms, their long-term use carries potential risks that should not be underestimated. Patients should work closely with their healthcare providers to develop a treatment plan that balances the benefits and risks, considering alternative options when appropriate. It is vital to prioritize both short-term relief and the long-term health and integrity of the skin when managing eczema. 


Why Curezma? 

Curezma is Australia's first patented non-steroidal eczema solution range. Our eczema regime offers an alternative to corticosteroids with no side effects. Our entire eczema product range has successfully undergone one of the largest clinical trials. Our Barrier Repair Serum is proven to repair the skin barrier function in just five days. It activates immunosurveillance pathways, enhancing the skin's natural immune response without suppressing it. This improves the production of anti-microbial peptides, promoting healing and a healthy skin immune system. 


Our Anti-Flare Oil reduces pruritus (severe itching), redness & inflammation instantly. Curezma treats both the symptoms and root causes of eczema, offering lasting relief without the side effects of corticosteroids. 


Don't settle for temporary solutions, reclaim your life with Curezma. 






https://www.webmd.com/skin-problems-and-treatments/psoriasis/topical-steroid-cream-withdrawal/ https://nationaleczema.org/eczema/treatment/topicals/